Drug-resistant 'superbugs' deemed urgent threats, CDC says

Antibiotic-resistant gonorrhea, a diarrhea-causing superbug and a class of fast-growing killer bacteria dubbed a "nightmare" were classified as urgent public-health threats in the United States on Monday.

According to a new report by the U.S. Centers for Disease Control and Prevention (CDC), at least 2 million people in the United States develop serious bacterial infections that are resistant to one or more types of antibiotics each year, and at least 23,000 die from the infections.

"For organism after organism, we're seeing this steady increase in resistance rates," Dr Thomas Frieden, director of the CDC, said in a telephone interview. "We don't have new drugs about to come out of the pipeline. If and when we get new drugs, unless we do a better job of protecting them, we'll lose those, also."

Overprescribing of antibiotics is a chief cause of antibiotic resistance, affording pathogens the opportunity to outwit the drugs used to treat them. Only a handful of new antibiotics have been developed and brought to market in the past few decades, and only a few companies are working on drugs to replace them.

In addition to resistant gonorrhea, the others now seen as urgent threats, according to the first-of-its-kind report released on Monday, are C. difficile and the killer class known as carbapenem-resistant Enterobacteriaceae, or CRE. Read more >>

Drug overdose deaths spike among middle-aged women

Overdose deaths in the U.S. are rising fastest among middle-aged women, and their drug of choice is usually prescription painkillers, the government reported Tuesday. "Mothers, wives, sisters and daughters are dying at rates that we have never seen before," said Dr. Thomas Frieden, director of the Centers for Disease Control and Prevention, which compiled the data.

The problem is one of the few health issues the CDC is working on that are clearly getting worse, he added. For many decades, the overwhelming majority of U.S. overdose deaths were men killed by heroin or cocaine. But by 2010, 40 percent were women - most of them middle-aged women who took prescription painkillers.

Skyrocketing female overdose death rates are closely tied to a boom in the overall use of prescribed painkillers. The new report is the CDC's first to spotlight how the death trend has been more dramatic among women.

The CDC found that the number and rate of prescription painkiller overdose deaths among females increased about fivefold 1999 to 2010. Among men, such deaths rose about 3 1/2 times. Read more >>